By H. Jecklin (auth.)

One thousand unselected sufferers with asthma were up for a standard interval of eleven years, with extremes of 33 years and 3 years. the common interval from the 1st indicators to the date of follow-up used to be 20.6 years within the 562 men and 22.3 years within the 438 adult females, with extremes of seventy two years and 3 years. in view that during the research no changes have been came upon among the sexes, they've been grouped jointly. phrases used, reminiscent of bronchial asthma, power bronchitis, youth bronchitis, age of onset, etc., were rigorously outlined, as have the descriptions of intermittent and non-stop bronchial asthma. the current country of the sufferers has been categorised as A (good), B (fair), C (poor), and D (dead). Early age of onset (before sixteen) and intermittent bronchial asthma have been linked and had a extra beneficial diagnosis, whereas the formative years bronchitic had a greater outlook than the grownup bronchitic. Intermittent and non-stop bronchial asthma were in comparison. The occurrence of bronchitis firstly was once larger within the non-stop staff, and the tendency to improve bronchitis through the years (present in all asthmatics) was once additionally larger within the non-stop crew. people with bronchitis have been in a lot poorer wellbeing and fitness on follow-up than these without.

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This phenomenon is connected with the fact that a rise in the blood nitrogen values increases the elimination of nitrogen, causing a normal decrease in waste products ("compensating retention", SARRE 1959). 60 mg 0/0 blood urea can be described as the critical limit. Nowadays endogenous creatinine is generally considered to be more reliable, since the blood urea content can be greatly influenced by the average albumin supply. Detailed investigations by MERTZ, SARRE and CREMER (1962) indicate a linear relationship between non protein nitrogen and the plasma concentration of endogenous creatinine.

The advantages of measuring blood pressure in both positions are obvious. e. a pulse rate of 56 or less per minute) may be induced by certain drugs. This sign is particularly suggestive when accompanied by a collapsing pulse in the upright position. (e) A swelling of the mucous membrane of the nose may suggest the use of reserpine or drugs of similar composition. This is not a very noticeable symptom. However, if this does come to the attention of the underwriter, and there are other signs or suspicions of antihypertensive treatment, the matter should be examined more carefully.

These may be called the daily averages. The Underwriting of Blood Pressure Abnormalities 35 (c) Form the average (arithmetic mean) of the daily averages for the past three months. This may be called the current average. e. those taken during the past five years, omitting those taken during the past three months. This may be called the past average. (e) Form the rating average by adding two thirds of the current average to one third of the past average. Subject to the reservations set out in paragraph (f) the rating average should be used as a basis for rating the risk.

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